Nairobi, Aug 22 (IANS) The United Nations Children’s Fund (Unicef) on Thursday appealed for $16.5 million to scale up mpox response in east and southern Africa.

UNICEF Regional Director for Eastern and Southern Africa, Etleva Kadilli, said in a statement issued in Nairobi, the capital of Kenya, that the new strain of mpox is a serious threat to vulnerable children and families, Xinhua news agency reported.

Children and vulnerable communities are on the verge of an expanding outbreak of mpox in the region as 200 confirmed cases have been detected across Burundi, Rwanda, Uganda, Kenya, and South Africa, the statement said.

“Aside from immediate lifesaving response, risk communication efforts and cross-border collaboration, investments in overall health system strengthening, continuity of essential services and targeted focus on programs that support overall child well-being must be prioritised,” Kadilli said.

The UN children’s agency warned concerns are rising over new public health emergencies as communities grapple with other ongoing crises. It said the new variant of the mpox virus (clade Ib) has been detected in all affected countries except South Africa, which is causing concern due to its potential for wider transmission across age groups, particularly young children.

Burundi has so far confirmed more than 170 mpox cases in 26 out of the 49 districts in the country, Unicef said.

It noted that children and adolescents aged below 20 years constitute nearly 60 per cent of cases detected, with children under five years old comprising 21 per cent of cases.

Kenya, Burundi, and Uganda have been struggling with multiple emergencies, including drought and floods, in addition to the immediate concerns posed by the virus, Unicef said.

The UN agency also warned concerns remain over the secondary impact of mpox outbreaks on children and adolescents, including stigma, discrimination, and disruptions to schooling and learning.

“Drawing from experiences gained during responses to HIV, Covid-19, and Ebola outbreaks, there must be a collective effort to prioritise plans for supporting survivors, combating stigma, and facilitating continuity of basic social services, especially learning and children’s reintegration into school and community,” Unicef said.

–IANS

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New Delhi, Aug 22 (IANS) Ozempic, the diet pill that took the world by storm has been under the public scanner for long, is found to be more devastating than what was originally speculated.

A study conducted at St. Vincent’s University Hospital (SVUH) in Dublin has challenged the prevailing belief that weight loss medications like Ozempic, Wegovy, or Monjaro primarily work by promoting satiety and reducing food intake.

The randomised controlled trial, led by Professor Donal O’Shea of SVUH and the UCD School of Medicine, involved 30 patients and focused on medications based on the hormone Glucagon-like peptide-1 (GLP-1).

The findings, published today in the Journal of the Obesity Society, reveal a strong relationship between increased metabolic activity caused by daily GLP-1 treatment and the amount of weight lost.

Interestingly, individuals with lower metabolic activity before beginning treatment experienced the most significant benefits.

“This study challenges the main narrative about these newer treatments, which is that they simply make you eat less and that any action on energy burn is minimal,” said O’Shea.

“The strength of the association is surprising given the relatively small number of participants, suggesting that this increase in metabolic activity is a significant contributor to how these drugs work.”

O’Shea emphasised the importance of understanding the full mechanism behind these treatments.

“Safe medical treatment for obesity is still in its infancy, and we need to fully understand how the treatment works. Understanding how these agents increase energy burn should be an important part of future research. The diet industry has been long criticised for the bilge and inhumanity it churns out in the name of making people slimmer, with the people in the public eye being the highest targets for it, actors, models etc, some of them being candid about their struggles to maintain the size zero figure. Studies like these throw a light on the uncomfortable part of pop culture.”

–IANS

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New Delhi, Aug 22 (IANS) The Supreme Court on Thursday asked the West Bengal Police not to disrupt the peaceful protests in the wake of the horrific incident at Kolkata’s R.G. Kar Medical College and Hospital, where a trainee doctor was raped and murdered earlier this month.

“We categorically reaffirm that peaceful protests shall not be disturbed and disrupted. The state shall not take any action against those who are peacefully protesting against the incident at state-run RG Kar Medical College and Hospital,” a bench presided over by CJI D.Y. Chandrachud said.

The Bench, also comprising Justices J.B. Pardiwala and Manoj Misra, told senior advocate Kapil Sibal, representing the West Bengal government, that the apex court has not injuncted the state police from exercising such lawful powers as entrusted in terms of law, clarifying that the protestors should also comply with the requirements of the law.

“Let the investigation continue,” it remarked, taking on record the status report filed by the Central Bureau of Investigation (CBI) as well by the Kolkata Police in relation to the vandalisation of the hospital premises on the night of August 14.

The Supreme Court also asked the jurisdictional court to decide, by 5 p.m. on Friday, the application of the investigative agency seeking permission for a polygraph test of the accused.

Further, it asked the National Task Force (NTF), set up by the government on its direction, to give a hearing to diverse medical associations while formulating effective recommendations relating to the safety, working conditions and well-being of doctors and medical professionals.

“To facilitate filing of suggestions before the NTF, we direct the Secretary in the Union Ministry of Health and Family Welfare to open a specific portal on the website of the ministry on which associations and different stakeholders may submit their suggestions for consideration before the committee,” the SC ordered.

Urging medical professionals across the country to return to work, the apex court assured the resident doctors and interns that no adverse action would be taken against them for participating in protests.

During the hearing, the CJI-led Bench observed: “Ask them (doctors) first to return to work. Once they return to work, nobody is going to take adverse action against the doctors. Let them first come back to work and then, if there is any difficulty, we will make sure that no adverse action is taken against the doctors.”

It added that “the poor people coming to hospital cannot be left behind in the lurch” and raised concerns about how public health infrastructure would run if doctors did not resume work.

The SC reiterated: “Let all doctors resume work. Please rest assured that once the doctors resume duty, then we will prevail upon the authorities to not take any adverse action.”

Asking all the state governments to address the safety concerns of doctors and medical professionals, the apex court directed the Union Ministry of Health & Family Welfare to convene a meeting with all the Chief Secretaries and Director Generals of Police within a period of one week.

–IANS

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New Delhi, Aug 22 (IANS) In order to better understand the changes that astronauts’ eyes undergo during spaceflights, doctors at Augusta University’s Medical College of Georgia (MCG) are working with Polaris Dawn, the first of three human spaceflight missions under the Polaris Program.

More than 70 per cent of astronauts experience these alterations, which are a component of a syndrome known as Spaceflight Associated Neuro-Ocular Syndrome (SANS), according to NASA.

SANS can cause a variety of symptoms, ranging from severe vision loss to the requirement for glasses.

In addition to advancing human spaceflight capabilities, the Polaris Program seeks to raise money and awareness for significant Earthly issues.

As a result of changes in bodily fluids like cerebrospinal fluid (CSF), which can result in structural alterations in the brain, astronauts may suffer changes in their vision as early as their first day in space, according to Dr. Matt Lyon, Director of the MCG Center for Telehealth.

While CSF floats upward in space and presses against the optic nerve and retina, gravity on Earth aids in its removal from the optic nerve sheath.

By using portable handheld ultrasound scanners, Lyon’s team hopes to identify the astronauts who are most vulnerable to SANS and comprehend the mechanisms underlying these alterations.

A technology first developed to explore the effects of high cranial pressure and mild traumatic brain injuries (TBIs), MCG has trademarked the idea of utilising portable ultrasound to visualise damage from pressure and fluid changes in the optic nerve sheath.

A $350,000 NIH funding enabled the researchers to work with URSUS Medical Designs LLC to build a 3-D ultrasound device.

Currently, astronauts are being screened with this technology to check for optic nerve sheath damage or incompetence, which Lyon believes could predispose them to SANS.

The crew of Polaris Dawn is being trained by the research team to utilise these ultrasonic instruments to assess fluid and pressure in real time while in orbit.

Determining whether the changes in vision are due to pressure, fluid volume, or both will aid in the development of countermeasures.

Using a lower-body negative pressure device, which draws bodily fluids downward, could be one way to mitigate the danger of SANS during space flights.

–IANS

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Visakhapatnam, Aug 21 (IANS) Fourteen workers were killed and 50 others injured in a reactor explosion in a pharmaceutical company in Andhra Pradesh’s Anakapalle district on Wednesday, officials said.

The explosion occurred during the lunch break at Escientia at Atchutapuram Special Economic Zone near Visakhapatnam.

A huge fire broke out following the explosion in the company premises, officials said. There was panic among workers, who ran out for safety.

A dozen fire tenders rushed to the spot to douse the fire. Initially, there were reports of seven deaths. However, the toll later rose sharply as the bodies of at least seven workers were found under rubble. Nine of the deceased were identified as plant AGM V. Satyanarayana, lab head Rami Reddy, chemist Harika, Parthasarthi, Y. Chinna Rao, P. Rajasekhar, Mohan, Ganesh, H. Prashanth and M. Narayan Rao.

Personnel of the National Disaster Response Force (NDRF), fire services personnel, and police rescued the workers trapped on the third floor of the building. The injured were shifted to various hospitals in Anakapalle and Visakhapatnam.

Officials said the death toll may go up as the condition of some of the injured was critical.

About 387 employees were present in the company at the time of the explosion. Such was the impact of the explosion that the bodies of the victims were blown to pieces. The slab of the first floor of the building also collapsed, trapping many workers under the rubble. The entire area was filled with thick smoke, hampering rescue operations.

The explosion also sent panic among people in the nearby villages.

Employees gathered outside the company demanding compensation for the victims, and punishment for the officials for their negligence. Angry workers were seen trying to stop ambulances carrying the bodies. One of the workers alleged that adequate safety precautions were not taken which resulted in the disaster. He said they had long been demanding for conduct of a safety audit at SEZ and alleged that the fire services department, inspector of factories, and Pollution Control Board failed to conduct the audit.

Chief Minister N. Chandrababu Naidu has expressed shock over the reaction explosion. He spoke to Anakapalle District Collector and enquired about the incident. He directed officials to ensure the best possible treatment for the injured. He wanted officials to use air ambulances to shift the injured to Hyderabad.

The Chief Minister will visit Anakapalle on Thursday. He will call on the injured at hospitals.

Former Chief Minister Y.S. Jagan Mohan Reddy also expressed his deep shock over the reactor explosion at Atchutapuram SEZ. He extended his heartfelt condolences to the families of those who lost their lives in the incident. The YSRCP chief has urged the government to ensure that the injured receive the best possible medical treatment in hospitals. He also called upon the authorities to take immediate steps to prevent such incidents in the future and demanded that the state government provide adequate support to the families of the deceased.

–IANS

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